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Co-Occurring Medical Conditions Caused by Substance Abuse
Substance abuse causes a wide range of both short- and long-term effects.
Annandale offers a robust onsite medical team who is involved in your care from the moment you arrive at our facility.
Read on to learn more about various health conditions caused by substance abuse, and how our approach to treatment works for you. One of the greatest risks is the lasting health conditions that develop as a result of substance abuse. Even legal substances like alcohol and nicotine can lead to serious health risks. Their prevalence in society makes them no less harmful than illicit substances like heroin or cocaine.
Questions? We’d love to talk!
Substance abuse affects every aspect of your mind and body, causing harmful and lasting health effects when left untreated.
Some of the conditions that drug and alcohol abuse causes include:
- Liver Damage
- Kidney Damage
- Heart Disease
- Cardiovascular Disease
- Lung Disease
- Diabetes
- Gastrointestinal Problems
Health Conditions Caused by Substance Abuse
Alcohol and drugs are harmful substances that cause extensive harm to the brain and body and multiple body systems are responsible for processing these substances. This means people who abuse drugs and alcohol not only risk their psychological well-being but the well-being of their entire body, too.2
Specific effects depend on a variety of factors, such as:
- Types of substances used
- Amount of substance used
- Frequency of abuse
- Length of abuse
- Method of use
- Age
- Gender
- Pre-existing health conditions
Long-term substance abuse can lead to a range of lasting health conditions. The severity of some conditions may lessen with sobriety, treatment, and time, while others are permanent.
Liver Damage
The liver’s primary function involves breaking down food into nutrients for the body. It is also responsible for detoxifying your body of substances like alcohol and drugs. Chronic substance use strains your liver and can lead to liver damage over time. Substances that cause liver damage include alcohol, heroin, and inhalants.3
Some examples of liver damage caused by substances include:
- Fatty liver: Enlargement of the liver which may cause mild discomfort. Almost all heavy drinkers develop fatty liver, but it is reversible if a person stops drinking early enough.4
- Alcoholic hepatitis: Swelling and inflammation of the liver, as well as the destruction of liver cells. Symptoms include fever, nausea, vomiting, jaundice, and abdominal pain.
- Cirrhosis: Scar tissue that builds up and replaces liver cells over time.
Kidney Damage
The kidneys are responsible for filtering substances and removing waste from the body. Kidney damage is one of the primary health conditions caused by substance abuse, especially after long-term use.5 Some of the drugs that can cause damage to the kidneys include:
- Heroin
- Alcohol
- Synthetic cannabis
- Ketamine
- Inhalants
- MDMA
- PCP
Kidney damage from substance abuse ranges from mild to severe and may result in renal failure that requires dialysis to treat.
Gastrointestinal Problems
Drugs ingested orally must be processed by the gastrointestinal system. This makes gastrointestinal problems some of the most common health conditions caused by substance abuse. Gastrointestinal problems range from mild to severe and can last both short- and long-term.
Alcohol abuse causes numerous harmful gastrointestinal problems including:15
- Nutritional deficiencies
- Gastrointestinal reflux disease (GERD)
- Pancreatitis
- Reflux esophagitis
- Mallory-Weiss tears (GI bleeding caused by ruptures in the lower esophagus)
- Increased risk of gastrointestinal cancer
Drugs also cause gastrointestinal problems when ingested orally.
- Opiates like prescription painkillers or heroin can cause severe constipation and stomach cramping. Many substances cause nausea and vomiting.
- Cocaine and methamphetamine are associated with a condition called mesenteric arterial vasospasm which can cause ischemic colitis or even bowel necrosis.16
Heart Disease
The heart is one of the most important organs in the body, responsible for sustaining life. Abusing substances of all kinds places incredible strain on the heart.6 Substances linked to greater risk for heart disease include:
- Alcohol
- Tobacco
- Prescription stimulants
- Methamphetamine
- Cocaine
- Heroin
Any substance that places strain on the heart is likely to be more problematic than helpful in the long run. In reality, heavy drinking can lead to numerous heart-related conditions, such as cardiomyopathy and coronary heart disease.
Cardiovascular Disease
Cardiovascular disease is an umbrella term that includes a range of heart- and blood vessel-related conditions. Most substances affect the heart’s ability to carry out its natural functions, often through increasing or decreasing blood flow in the body.
- Long-term alcohol abuse is typically associated with a high risk of conditions like hypertension and arrhythmia.7
- Stimulants like cocaine, methamphetamine, and prescription amphetamines immediately impact blood pressure, placing people at risk of heart palpitations, heart attack, or cardiac arrest.
- Heroin and other opioids decrease heart rate which reduces cardiac output and can cause arrhythmias and noncardiac pulmonary edema.8
Lung Disease
Some of the health conditions caused by substance abuse include a variety of respiratory problems. Different substances have different effects on the respiratory system, so specific conditions depend on the type or types of substances a person uses.
- Alcohol abuse is responsible for multiple types of respiratory problems, including lung infections (i.e. pneumonia) and acute respiratory distress syndrome9
- Central nervous system depressants (particularly opioids) cause slow, shallow, or irregular breathing.10
- Opioid overdose can cause slow breathing to the point of respiratory arrest. Oxygen deprivation caused by this slowed breathing over a long period may lead to damage to other organs.
- Smoking any type of substance can cause lung damage and leave the respiratory system more at risk of conditions like bronchitis and emphysema.11
Diabetes
Not many people realize that diabetes is another example of the health conditions caused by substance abuse.
- Alcohol and drug abuse increase the risk of developing diabetes, caused by the effects of substances on glucose homeostasis as well as the increase in cell damage.14
- Substance abuse can worsen diabetes in those who are already diabetic before using substances.
- Blood sugar fluctuations caused by insulin injections can increase drug cravings.
Mental Health Disorders
Mental health disorders are another common health condition caused by substance abuse.
Drugs and alcohol directly affect brain chemistry and functioning which can alter the ways people feel, think, and act. Long-term use can lead to lasting changes that affect natural levels and the production of neurotransmitters like dopamine, norepinephrine, serotonin, and more.17
Substances have an extensive impact on overall psychological well-being which may result in the development of a mental health disorder. Conditions like depression, anxiety, and bipolar disorder are common among people who abuse drugs and alcohol. Once symptoms develop, people then continue using substances to find relief from their effects. This creates an ever-worsening spiral that can only be helped by intervention and substance abuse treatment.
Annandale Behavioral Health is here for you each step of the way
To learn more about our programs, reach out today! Our admissions team is ready to help.
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24/7 Comprehensive Care
Our residential setting provides round-the-clock support, medical detox when needed, and structured days designed to build stability and healthy routines.
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Safe & Supportive Environment
Clients heal in a fully supervised space, free from outside triggers and distractions, ensuring the focus stays on recovery and long-term personal growth.
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More Than Outpatient or Rehab-Only
Unlike outpatient care, our program offers full residential treatment—combining medical support, therapy, and daily structure for lasting results.
Effective Treatment for Co-Morbid Conditions in Pasadena, CA
Some health conditions caused by substance abuse can be relieved or reversed following the elimination of drugs and alcohol. Others have effects that last long past the final high. Ultimately, effective treatment for substance-related health conditions requires clinicians to take a case-by-case approach.
At Annandale Behavioral Health we are staffed with medical personnel at all times. This includes nursing staff and physicians who are double board-certified in both addiction and internal medicine. This allows our team to create highly individualized treatment programs for those who experience co-morbid conditions, meaning the presence of both a substance use disorder and a health condition.
You should always consult your primary care physician before seeking specific treatment if you’re experiencing any substance-related health conditions. They will work with the necessary parties to provide an informed approach to your care.
Find Freedom From Substance Abuse, the Annandale Difference
Annandale Behavioral Health is an evidence-based addiction treatment program that paves the way for individuals seeking sobriety. If you’ve struggled with your substance use, we’re here to help. Whether you’ve been to treatment before or this is your first time looking to stop, we have a program that is right for you.
Our private recovery clinic in Pasadena, CA integrates evidence-based addiction treatment with dual diagnosis therapies. We include long-standing, proven approaches such as cognitive behavioral therapy, dialectical behavior therapy (DBT), and Motivational Interviewing (MI). Find healing through a treatment plan tailored to you, using methods that best support your recovery.
Annandale offers a robust onsite medical team who is involved in your care from the moment you arrive at our facility. Our comprehensive continuum of care sets you up for success in sobriety, from medical detox through Annandale Post, our unique approach to recovery aftercare services.
RESOURCES
- Substance Abuse and Mental Health Services Administration. (2020). 2020 National Survey on Drug Use and Health.
- National Institute on Drug Abuse. (2017). HealthConsequencesofDrug Misuse.
- National Institute on Drug Abuse. (2017). Liver Damage.
- Mayo Clinic Health System. (2021). What effect does alcohol have on your health – and your liver?.
- National Institute on Drug Abuse. (2017). KidneyDamage.
- National Library of Medicine. (2014). Substance Use and Associated Health Conditions throughout the Lifespan.
- National Institute on Alcohol Abuse and Alcoholism. (2001). Alcohol’s Effects on the Risk for Coronary Heart Disease.
- National Library of Medicine. (2003). Cardiovascular manifestations of substance abuse: part 2.
- National Library of Medicine. (2008). Alcoholic Lung Disease.
- National Institute on Drug Abuse. (2018). What classes of prescription drugs are commonly misused?.
- National Institute on Drug Abuse. (2017). RespiratoryEffects.
- Mayo Clinic. (2020). COPD.
- Centers for Disease Control and Prevention. (2020). An Update on Cancer Deaths in the United States.
- National Library of Medicine. (2018). The Effects of Substance Abuse on Blood Glucose Parameters in Patients with Diabetes.
- National Library of Medicine. (2017). Alcohol and Gut-Derived Inflammation.
- Miller, S. C., Fiellin, D. A., Rosenthal, R. N., & Saitz, R. (2019). The ASAM Principles of Addiction Medicine, Sixth Edition. Philadelphia: Wolters Kluwer.
- National Institute on Drug Abuse. (2017). Impact of Drugs on Neurotransmission.
Your Journey to Recovery Starts Here!
You deserve care that respects your privacy and supports your healing. We’re here to guide you every step of the way!
Giorgio Albanese
18:55 07 May 25
Annandale helped change my life. The clinical programming helped me tremendously and the house felt like a home. The environment was safe and comfortable. My life has improved significantly and the internal awareness I've gained has followed me into my work, my fellowship, and my marriage. I cannot thank the staff enough for helping me get back on my feet. I will recommend this facility to anyone that comes to me for help.
Chloe Nett
20:27 05 May 25
Darryl and Remy are both incredible and run a tight program that is highly ethical. Changed my life!
Larkin Hill
23:41 03 May 25
Be wary of one star reviews for treatment centers. There are some vindictive, bitter, angry clients who will blame anyone but themselves; and treatment centers and their staff tend to be a go-to target for abuse and retaliation.
In short, Annandale worked for me.
Short story made long: Like any treatment center, you will get out what you put in though. But a good treatment center will give you all the tools, support and understanding you need. And that is what Annandale provides: a structure and foundation for your success, which you build on once you leave.
All the various treatment center bells, whistles and accoutrements don’t matter without a good staff/therapists on hand to guide and support. Luckily, Annandale has both.
The program itself focuses not only on getting sober/maintaining sobriety, but also on modifying negative thought patterns and the troublesome behavior that arises as a result. They know that you must focus on the problem itself, not just the symptoms, in order to recover. Drinking is a symptom of a deeper rooted issue.
They also offer some unique elements to the program, such as equine therapy and soundbaths. I scoffed initially, but kept an open mind. And guess what? It was a great help. Other groups/activities included yoga, meditation, mindfulness walks, nature walks, art, gardening, etc. They take you to 12 step recovery meetings, but Annandale itself is non-denominational as far as I could gather. Which is a plus in my book.
Great location in Pasadena. Right up the street from the Rose Bowl, where you’ll take walks some days. Other walks go a block or two in the other direction and offer absolutely breathtaking panoramic views of the Rose Bowl, Pasadana and its environs, mountain ranges etc. It’s truly a sight to behold.
The house and its campus are extremely serene and quiet. The house is comfortable, a comfy “home” vibe with people that genuinely care. A special feeling to it. Doesn’t feel like some “facility”.
Private bedrooms with their own flat screen TVs. Almost all have their own private bathroom. You get to place takeout lunch and dinner choices (with a mind towards healthy options from some great restaurants) on the iPad every day (which is included with your stay).
But more than anything, it is the staff that makes or breaks the place. Darryl is the owner and possibly the first person you’ll speak to. a very kind, caring, genuine, astute and just cool guy. Very helpful and personable. I was in a bad way when I initially called and Darryl was an immeasurable help in easing my concerns and providing comfort in a very distressful time in my life. Remy, the on-site nurse, is extremely attentive and understanding. Dr Coe is one of the most brilliant doctors I’ve ever had the pleasure of speaking with—the guy pulled things out that shocked me, things that no doctor-therapist/psychiatrist has been able to reach or decipher in all my years. He gave me a true, unbridled diagnosis of where my issues stemmed from. My wife of 20 years co-signed what he said with a very troubling passion (haha). Said he was spot-on, and he was.
Roxanne is one of the kindest and most lovely people I’ve ever met. The most gentle eyes, emphatic tone — a truly calming presence who offered me immeasurable support so thank you 🙏. Jordan was relatable, friendly and easy to talk to. Very intelligent and understanding of how addiction and sobriety work. Kevin, one of the nicest guys I’ve ever met. Michael, who became a genuine friend and somebody I could always talk to — and was always willing to listen.
Becky, Carrie, Xenia, Alex, Chris and I know I’m missing a few, but really, everyone was great and offered their own unique approach/personality. This place quite literally saved my life. I was on death’s door and couldn’t even walk in my own when I went in. And walked out a “new’ man.
In short, Annandale worked for me.
Short story made long: Like any treatment center, you will get out what you put in though. But a good treatment center will give you all the tools, support and understanding you need. And that is what Annandale provides: a structure and foundation for your success, which you build on once you leave.
All the various treatment center bells, whistles and accoutrements don’t matter without a good staff/therapists on hand to guide and support. Luckily, Annandale has both.
The program itself focuses not only on getting sober/maintaining sobriety, but also on modifying negative thought patterns and the troublesome behavior that arises as a result. They know that you must focus on the problem itself, not just the symptoms, in order to recover. Drinking is a symptom of a deeper rooted issue.
They also offer some unique elements to the program, such as equine therapy and soundbaths. I scoffed initially, but kept an open mind. And guess what? It was a great help. Other groups/activities included yoga, meditation, mindfulness walks, nature walks, art, gardening, etc. They take you to 12 step recovery meetings, but Annandale itself is non-denominational as far as I could gather. Which is a plus in my book.
Great location in Pasadena. Right up the street from the Rose Bowl, where you’ll take walks some days. Other walks go a block or two in the other direction and offer absolutely breathtaking panoramic views of the Rose Bowl, Pasadana and its environs, mountain ranges etc. It’s truly a sight to behold.
The house and its campus are extremely serene and quiet. The house is comfortable, a comfy “home” vibe with people that genuinely care. A special feeling to it. Doesn’t feel like some “facility”.
Private bedrooms with their own flat screen TVs. Almost all have their own private bathroom. You get to place takeout lunch and dinner choices (with a mind towards healthy options from some great restaurants) on the iPad every day (which is included with your stay).
But more than anything, it is the staff that makes or breaks the place. Darryl is the owner and possibly the first person you’ll speak to. a very kind, caring, genuine, astute and just cool guy. Very helpful and personable. I was in a bad way when I initially called and Darryl was an immeasurable help in easing my concerns and providing comfort in a very distressful time in my life. Remy, the on-site nurse, is extremely attentive and understanding. Dr Coe is one of the most brilliant doctors I’ve ever had the pleasure of speaking with—the guy pulled things out that shocked me, things that no doctor-therapist/psychiatrist has been able to reach or decipher in all my years. He gave me a true, unbridled diagnosis of where my issues stemmed from. My wife of 20 years co-signed what he said with a very troubling passion (haha). Said he was spot-on, and he was.
Roxanne is one of the kindest and most lovely people I’ve ever met. The most gentle eyes, emphatic tone — a truly calming presence who offered me immeasurable support so thank you 🙏. Jordan was relatable, friendly and easy to talk to. Very intelligent and understanding of how addiction and sobriety work. Kevin, one of the nicest guys I’ve ever met. Michael, who became a genuine friend and somebody I could always talk to — and was always willing to listen.
Becky, Carrie, Xenia, Alex, Chris and I know I’m missing a few, but really, everyone was great and offered their own unique approach/personality. This place quite literally saved my life. I was on death’s door and couldn’t even walk in my own when I went in. And walked out a “new’ man.
judy hiep
20:08 02 Feb 24
I love this place. I had to check my niece in 2 years ago. It was a difficult time for our family. Remy explained everything step by step and reassured us she will be in good hands. Like most family, this is our first time having to figure things out. The Facility and staff were very sweet and knowledgeable. The place is like a sanctuary. Peaceful, well thought out and comfortable. We are forever thankful what they have done for us, and appreciate everyone on the team.
Zorina Pelant
16:21 26 Jan 24
Remy Olivier is wonderful. She is the Program Director at Annandale. She is caring, conscientious and so knowledgeable. She makes multiple arrangements and was always available to assist with anything that came up. Remy is an RN who has worked in behavioral health for many years and uses her nursing skills and knowledge of addition when dealing with patients. I can’t say enough nice things about her.
Annandale is owned and operated by Remy and her husband Darryl, who has also been working in the field for 30 years. You can expect outstanding clinical care in a program that is family owned.
Annandale is owned and operated by Remy and her husband Darryl, who has also been working in the field for 30 years. You can expect outstanding clinical care in a program that is family owned.
Alan Coe
03:26 26 Jan 24
Fantastic Rehab with intelligent, compassionate, and knowledgeable staff. This is easily the best facility in all of Los Angeles. Remy is the kindest and most supportive person I have ever met.
Samantha Myles
03:02 07 Dec 23
First class medical detox - the level of experience, compassion and care is unmatched. They are a hands-on, genuine team who truly treats their clients like their own family. Brendan and Remy have been a pleasure to work with. I would send my own family members to Elevate Wellness Center.
Morgan Vandewater
16:34 07 Apr 23
Elevate is a wonderful place. Treatment is tailored to each individual and the staff is absolutely wonderful. I would highly recommend this place for residential treatment. It is an incredibly calming and motivating environment to recover in.
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Our Medical & Clinical Treatment Team
Annandale Behavioral Health offers a highly experienced and trained treatment team to help you or your loved one safely detox from substances and design a customized aftercare plan to maintain sobriety. Our comprehensive treatment team includes Case Managers, Individual Therapists, RNs, LVNs, Psychiatrists, and more.
Darryl Olivier
Founder and Chief Executive Officer
Remy Olivier, RN
Founder and Program Director
Jennifer Bembry
Founder and Chief Medical Officer
Eric Bembry
Founder and Chief Financial Officer
Tour Our Addiction Treatment Facility
Annandale Behavioral Health is located in a contemporary farmhouse situated on the sprawling grounds in one of Pasadena’s most beloved neighborhoods. This intimate recovery setting has just six beds, allowing for a higher level of care within a safe, supportive treatment environment. The park-like setting features beautiful gardens and an outdoor fireplace that enhances the serene atmosphere.
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